Cannabis License (COFEPRIS)

Workflow steps

1. License Intent
   2017 constitutional reform allowed medical use of cannabis in Mexico. 2021 Supreme Court declared recreational prohibition unconstitutional. Regulatory framework for adult-use market still developing as of 2026. COFEPRIS issues manufacturing permits.
   • 2017 constitutional reform (medical use)
   • 2021 Supreme Court ruling (recreational)
   • COFEPRIS manufacturing permit application
   • Adult-use framework still developing
2. COFEPRIS Manufacturing Permit Application
   Apply to COFEPRIS for a cannabis manufacturing permit. Application includes facility details, BPF compliance plan, product specifications, and security documentation.
   • Completed COFEPRIS application
   • Facility details and BPF compliance plan
   • Product specifications
   • Security and chain-of-custody documentation
   • Financial solvency requirements
3. Permit granted?
   COFEPRIS evaluates the manufacturing permit application. Mexico's cannabis regulatory environment is evolving — processing times and requirements may shift as the adult-use framework develops.
4. Address COFEPRIS Queries
   Respond to COFEPRIS requests. Common issues: BPF compliance gaps, security deficiencies, or incomplete product documentation.
   • BPF compliance remediation
   • Updated security documentation
   • Revised product specifications
5. Manufacturing Permit Granted ✓
   COFEPRIS manufacturing permit issued. Permit holder may manufacture cannabis products under BPF standard. Adult-use market regulatory framework still developing as of 2026.