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Magistral Formula (Fórmula Magistral)

Primary patient access pathway in Spain — pharmacy compounding

General Verified 2026-04-20

Workflow steps

  1. Patient Need
    Magistral preparation (Fórmula Magistral) is the PRIMARY patient access pathway in Spain. Physicians prescribe; pharmacies compound cannabis formulations from imported pharmaceutical-grade cannabis. Sativex is the only nationally authorized cannabis medicine. Cannabis clubs operate in legal grey area (Barcelona, Catalonia) — NOT the official pathway.
    • Physician prescription
    • Cannabis formula specified
  2. Physician Prescribes Cannabis Formula
    Physician prescribes a specific cannabis formula (Fórmula Magistral) for the patient. Prescription specifies active ingredients, dosage form, and strength.
    • Medical prescription
    • Cannabis formula composition specified
    • Indication documented
  3. Pharmacist Evaluates Magistral Preparation
    Compounding pharmacist evaluates feasibility of the prescribed formula. Assesses availability of pharmaceutical-grade cannabis and other ingredients.
    • Spanish pharmacy license
    • Magistral preparation capability
    • Formula viability assessment
  4. Product / ingredients available?
    Pharmacist determines whether pharmaceutical-grade cannabis and other ingredients are available from authorized importers.
  5. Authorized Importer Supplies Cannabis
    Authorized importer provides pharmaceutical-grade cannabis to the compounding pharmacy. Importer must have AEMPS import authorization.
    • AEMPS import authorization
    • EU-GMP compliant supply
    • Pharmaceutical-grade cannabis
  6. Pharmacist Compounds Formula
    Pharmacist compounds the prescribed cannabis formula (Fórmula Magistral) according to the prescription. Quality controls applied per magistral preparation standards.
    • Formula prepared per prescription
    • Quality control per magistral standards
    • Labeling and patient instructions
  7. Patient Receives Formula ✓
    Compounded cannabis formula dispensed to patient. Follow-up with prescribing physician required.
GMP Pathway